Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier.

نویسندگان

  • Huihui Yan
  • Jiyao Wang
  • Peiwei Yi
  • Hao Lei
  • Changyou Zhan
  • Cao Xie
  • Linglin Feng
  • Jun Qian
  • Jianhua Zhu
  • Weiyue Lu
  • Cong Li
چکیده

A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

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عنوان ژورنال:
  • Chemical communications

دوره 47 28  شماره 

صفحات  -

تاریخ انتشار 2011